Abstract

Radiation-induced cavernous hemangioma (RICH) is a possible complication of brain irradiation. These lesions are rare; only a few radiation-induced cavernous hemangioma cases have been published to date. We report a case of a 41-year-old female who was diagnosed with metastatic breast cancer in 2012 and subsequently underwent metastatic brain tumor excisions followed by multiple brain irradiation sessions and stereotactic radiosurgery. In 2023, she presented with symptoms of worsening memory, left-sided weakness, and cerebellar signs. Brain imaging revealed lesions at the two sites of previous surgeries and radiation, so she underwent new brain lesion excisions to control the symptoms. Pathological inspection of the lesions showed multiple radiation-induced cavernous hemangiomas with no residual or recurrent tumor. Herein we report the details of this case and discuss the typical clinical and histological features of radiation-induced cavernous hemangiomas.