Abstract

Background: Oral cancer and its treatments are linked to several common psychosocial symptoms, such as cancer-related fatigue and anxiety, which affect quality of life. Aim: The study sought to assess the effectiveness of comprehensive nursing intervention on postoperative fatigue, anxiety, and quality of life in patients with oral cancer. Methods: We investigated the level of fatigue, anxiety, and quality of life of 180 postoperative oral cancer patients who were randomized into 90 experimental and 90 control groups. Following the nursing intervention, multidimensional fatigue inventory (MFI-20), Beck anxiety inventory (BAI) scale, and the European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) tools were used to assess the level of fatigue, anxiety, and quality of life, respectively. Results: The study included 180 participants, with 61.7% males and 38.3% females. Significant reductions in general, physical, and mental fatigue were observed in the experimental group (p<0.01), along with improvements in role function, cognitive function, emotional status, social functioning, and overall quality of life (p<0.05). The only significant differences observed in the control group were reduced activity and general symptoms. Post-intervention, the experimental group showed marked improvements in fatigue, anxiety, and quality of life. Conclusions: This research highlights the significant impact of comprehensive nursing interventions in alleviating postoperative fatigue and anxiety while improving the quality of life in postoperative oral cancer patients. It is suggested that such interventions be implemented to help oral cancer patients deal with the temporary deterioration that occurs following surgery.